María Isabel Rodríguez-Franco Selected Research

Glutamates

4/2017	Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
11/2009	Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.

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María Isabel Rodríguez-Franco Research Topics

Disease

21	Alzheimer Disease (Alzheimer's Disease) 12/2019 - 01/2006
7	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2019 - 12/2010
6	Neuroblastoma 02/2015 - 05/2009
2	Pancreatitis 01/2021 - 10/2020
2	Brain Ischemia (Cerebral Ischemia) 04/2017 - 09/2013
2	Stroke (Strokes) 04/2017 - 01/2012
1	Inflammation (Inflammations) 01/2022
1	Pain (Aches) 01/2021
1	Nervous System Diseases (Neurological Disorders) 05/2020
1	Brain Diseases (Brain Disorder) 01/2017
1	Infarction (Infarctions) 09/2013
1	Memory Disorders (Memory Loss) 09/2013

Drug/Important Bio-Agent (IBA)

7	AntioxidantsIBA 10/2016 - 01/2006
6	MelatoninIBA 02/2015 - 01/2006
5	Cholinergic Agents (Cholinergics)IBA 05/2014 - 05/2009
4	Neuroprotective AgentsIBA 12/2015 - 06/2011
3	Oxidoreductases (Dehydrogenase)IBA 01/2022 - 10/2016
3	Okadaic AcidIBA 01/2022 - 06/2011
3	Biological ProductsIBA 12/2019 - 08/2012
3	Cholinesterases (Cholinesterase)IBA 12/2019 - 10/2016
3	LigandsIBA 10/2018 - 09/2013
3	AminesIBA 02/2015 - 08/2012
3	Pharmaceutical PreparationsIBA 09/2014 - 05/2009
3	Tacrine (Cognex)FDA Link 08/2012 - 01/2006
2	Epoxide HydrolasesIBA 01/2021 - 10/2020
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 05/2020 - 01/2017
2	Monoamine Oxidase (MAO)IBA 10/2018 - 12/2015
2	Donepezil (Aricept)FDA LinkGeneric 08/2018 - 04/2017
2	EnzymesIBA 08/2018 - 06/2012
2	GlutamatesIBA 04/2017 - 11/2009
2	Free RadicalsIBA 12/2015 - 12/2010
2	tacrine-8-hydroxyquinolineIBA 06/2012 - 07/2010
2	AcetylcholinesteraseIBA 06/2012 - 01/2006
1	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	CeruletideIBA 01/2021
1	LactamsIBA 05/2020
1	diazonaphthalenedisulfonic acid (NDS)IBA 12/2019
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2019
1	sigma Receptors (sigma Receptor)IBA 12/2019
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 10/2018
1	ChromonesIBA 10/2018
1	FlavonoidsIBA 08/2018
1	Calcium Channels (Calcium Channel)IBA 04/2017
1	Glucose (Dextrose)FDA LinkGeneric 04/2017
1	Oxygen (Dioxygen)IBA 04/2017
1	inulin trinicotinate monomethochloride (L-3)IBA 04/2017
1	AlkaloidsIBA 01/2017
1	Memantine (Namenda)FDA Link 01/2017
1	Amyloid beta-PeptidesIBA 02/2015
1	2- chloro- 5,6- dihydro- 5,6- diacetyldibenzo(b,f)(1,4,5)thiadiazepineIBA 09/2014
1	AcidsIBA 08/2014
1	CurcuminIBA 08/2014
1	AmidesIBA 08/2014
1	dibenzo(1,4,5)thiadiazepineIBA 06/2014
1	N- ((5- (3- (1- benzylpiperidin- 4- yl)propoxy)- 1- methyl- 1H- indol- 2- yl)methyl)- N- methylprop- 2- yn- 1- amineIBA 10/2013
1	Scopolamine (Hyoscine)FDA Link 09/2013
1	ethyl 5- amino- 2- methyl- 6,7,8,9- tetrahydrobenzo(b)(1,8)naphthyridine- 3- carboxylateIBA 09/2013
1	Muscarinic AntagonistsIBA 09/2013
1	Galantamine (Galanthamine)FDA LinkGeneric 09/2013
1	Trace Elements (Biometals)IBA 06/2012
1	Amyloid (Amyloid Fibrils)IBA 02/2012
1	nitronesIBA 01/2012
1	quinolineIBA 01/2012
1	Peptides (Polypeptides)IBA 06/2011
1	CalciumIBA 06/2011
1	phenothiazineIBA 12/2010
1	CopperIBA 07/2010
1	RotenoneIBA 05/2009

Therapy/Procedure

1	Therapeutics 12/2010